Joshua D. Rabinowitz
EDUCATION
Stanford University
M.D., 2001
Ph.D. in Biophysics, 1999
University of North Carolina at Chapel Hill
B.A. with Highest Honors in Mathematics, 1994
B.A. in Chemistry, 1994
RESEARCH POSITIONS
Princeton University
Ludwig Institute for Cancer Research, Princeton Branch
Director, 2021-present
Department of Chemistry & Lewis-Sigler Institute for Integrative Genomics
Professor, 2011–present
Associate Professor, 2009–2011
Assistant Professor, 2004–2009
Department of Molecular Biology
Associated Faculty, 2005–present
Rutgers Cancer Institute of New Jersey, Member, 2008-
Alexza Pharmaceuticals
Co-founder and Vice President, Research, 2000–2004
- Accelerating onset of drug action through thermally generated aerosols
HONORS, AWARDS, AND FELLOWSHIPS
Allen Distinguished Investigator, 2019
NIH Pioneer Award, 2016
Agilent Thought Leader Award, 2013
Kavli Frontiers of Science Scholar, Kavli Foundation and National Academy of Sciences, 2008
CAREER Award, National Science Foundation, 2007–2013
Beckman Young Investigator Award, Arnold and Mabel Beckman Foundation, 2005–2009
Medical Scientist Training Program (MSTP) Trainee, National Institutes of Health, 1994–2001
Churchill Fellow (Declined), 1994
Barry M. Goldwater Scholar, Federal Excellence in Education Foundation, U.S. Federal Government, 1993–1994
President, Phi Beta Kappa, University of North Carolina, 1993–1994
Herbert Worth Jackson Scholar, University of North Carolina Honors Program, 1990–1994
PUBLICATIONS
See publications tab.
RECENT INVITED TALKS
Indiana University School of Medicine (2023)
CSHL, Mechanisms of Metabolic Signaling Conference (2023)
Oncology Society of NJ (2023)
Yale University, Endocrine Grand Rounds (2023)
University of Utah (2023)
UC Berkeley, CA (2023)
Keystone, Adipose Tissue: Energizing Good Fat/Bioenergetics in Health & Diseases (2023)
Translational Genomics Research Institute (TGEN) (2023)
Georgetown University, Center for Metabolomic Studies (2022)
Harvard Medical School, Marianne Wessling-Resnick Distinguished Lecture (2022)
Nature Conference, “Metabolic communication across biological scales” (2022)
EACR Conference on Cancer Metabolism (2022)
Ludwig Distinguished Seminar, Lausanne (2022)
Allen Frontiers Symposium (2022)
Metabolism Meets Epigenetics Symposium, EMBO|EMBL (2021)
University Lecture Series, UT Southwestern (2021)
Cancer Biology Program Seminar, Stanford (2021)
NIH High-Risk, High-Rewards Research Symposium (2021)
Korean Society for Biochemistry & Molecular Biology International Conference (2021)
25th United Mitochondrial Disease Foundation Anniversary Symposium (2021)
Pfizer 13th Annual Frontiers Symposium (2021)
American Association for Cancer Research, Annual Meeting (2021)
Keystone Symposia on Metabolic Decisions in Development and Disease (2021)
Salk T32 Cancer Day Symposium (2021)
Kansas University Cancer Center (2021)
Metabolomics Workshop by Cluster of Excellence PMI (2021)
RCINJ Cancer Research Symposium (2020)
AACR Special Conference on Epigenetics & Metabolism (2020)
US Oncology Research, Virtual Annual Science Forum (2020)
2020 International Congress of Diabetes and Metabolism
Conference of the Metabolomics Association of North America (2020)
FASEB Research Conference on Folic Acid, Vitamin B12, & One-Carbon Metabolism (2020)
American Diabetes Association, 80th Scientific Sessions (2020)
NYAS Cancer Metabolism & Signaling Conference Keynote (2020)
Keystone Symposia on Diabetes (2020)
Beth Israel Deaconess Medical Center and Harvard Medical School (2019)
UNC Lineberger Comprehensive Cancer Center (2019)
Harvard Medical School, Dept. of Genetics (2019)
18th Annual Science Forum, US Oncology Research (2019)
Morgridge Institute for Research, University of Wisconsin-Madison (2019)
American Association for Cancer Research, Atlanta (2019)
Keystone Symposia, Tumor Metabolism (2019)
Memorial Sloan Kettering Cancer Center (2019)
Peking University (2019)
Northwestern University (2018)
American Association for Cancer Research, Metabolism and Cancer, Brooklyn (2018)
Forbeck Focus Meeting, Epigenetics and Metabolism, Geneva (2018)
Abcam Cancer & Metabolism, Cambridge (2018)
American Association for Cancer Research, Chicago (2018)
Calico Labs (2018)
University of Pennsylvania (2018)
EMBO Symposium on Systems Biology, Heidelberg (2017)
Shanghai Jiao Tong University (2017)
Weill Cornell Metabolomics Summit (2017)
Caltech, Novartis Symposium (2017)
University of Washington (2017)
University of California-Sacramento, Comprehensive Cancer Center (2017)
University of California-Davis, West Coast Metabolomics Center (2017)
NYU, Center for Genomics and Systems Biology Symposium (2017)
CSHL, Mechanisms of Metabolic Signaling Meeting (2017)
University of CO, Denver, Dept. of Biochemistry & Molecular Genetics (2017)
Keystone Symposium on Tumor Metabolism (2017)
CSHL, Chemistry & Metabolism Meeting (2017)
University of California-Los Angeles, David Geffen School of Medicine (2016)
New York Academy of Science (2016)
Rutgers University, Boxer Lecture (2016)
American Association for Cancer Research, New Orleans (2016)
Parker Institute for Cancer Immunotherapy Retreat (2016)
New Frontiers in Understanding Tumor Metabolism/Immunometabolism
in Immune Function & Inflammatory Disease, Banff, Alberta (2016)
Pfizer, Cardiovascular & Metabolic Disease Research Unit (2015)
Ludwig Cancer Research Center, Inaugural Symposium, Harvard (2015)
US Oncology Network Clinical Science Meeting, Dallas (2015)
Stanford, University, Chemical & Systems Biology Dept. (2015)
American Association for Cancer Research, Philadelphia (2015)
Metabolism, Diet and Disease: Cancer and Metabolism (2014)
American Association for Cancer Research (2014)
Yale University, Department of Chemistry (2013)
University of Pennsylvania, Dept. of Biochemistry & Biophysics (2013)
Cancer Research UK, Cambridge University (2013)
University of Pennsylvania, ITMAT Symposium (2013)
Harvard Medical School, Dept. of Systems Biology (2013)
Duke University School of Medicine, Depts. of Pharmacology & Cancer
Biology (2013)
Cancer Institute of New Jersey (2013)
Systems Biology of Infection Symposium, Switzerland (2013)
MIT, Koch Institute for Integrative Cancer Research (2013)
American Society for Microbiology (2013)
American Society for Biochemistry and Molecular Biology Conference (2013)
Keystone Symposium on Tumor Metabolism (2013)
University of Chicago (2012)
United Mitochondrial Disease Foundation (2012)
Memorial Sloan-Kettering Cancer Center (2012)
American Association for Cancer Research, Annual Meeting (2012)
New York Academy of Science (2012)
AFOSR Bioenergy Program Review (2011)
CONO 2011 / Viral Ed Conference (2011)
Rockefeller University (2011)
SU2C Team Meeting (2011)
PhytoMetaSyn Project, Annual Meeting (2011)
Broad Institute (2011)
NJ Governor’s Conference on Effective Partnering in Cancer Research (2011)
Case Western University (2011)
International Conference on Systems Biology, Edinburgh (2010)
Metabolomics Society, Amsterdam (2010)
IEEE International Conference on Bioinformatics & Bioengineering (2010)
American Association for Cancer Research, Washington, DC (Speaker & Session Chair) (2010)
New York Academia of Sciences, Hot Topic Symposium, Learning from the Metabolome (2010)
Department of Energy, Genomic Sciences Meeting (Plenary Speaker) (2010)
Cold Spring Harbor Laboratory (2009)
National Institutes of Health, Cancer Cell Metabolism Workshop (2009)
Dana Farber Cancer Institute, Kidney Cancer Program
(Keynote Speaker) (2009)
University of Pennsylvania, Institute for Diabetes,
Obesity & Metabolism (2009)
University of Tennessee, Department of Chemistry (2009)
Vanderbilt University, Institute of Chemical Biology (2009)
Stanford University, Department of Bioengineering (2008)
University of California-Berkeley, Department of Microbiology (2008)
Harvard University, Medical School, Department of Cell Biology (2008)
University of California-San Diego, Department of Bioengineering (2008)
Institute for Advanced Study, Department of Systems Biology (2008)
University of Pennsylvania, Medical School, Cancer and Diabetes Metabolism
Seminar (2008)
Scripps Research Institute, Center for Mass Spectrometry (2008)
Harvard University, FAS Center for Systems Biology (2008)
INVENTORSHIP
Inventor of 160 patents issued by U.S. Patent and Trademark Office
Inventor of five drug products in FDA-sanctioned clinical testing.
- The most advanced product treats acute agitation in bipolar and
schizophrenic patients. It has successfully completed two phase 3
clinical trials and will be submitted for FDA approval shortly.
- The other products (several of which are in Phase II trials) treat migraine
headache, panic attacks, insomnia, and cancer pain.
ACTIVE GRANTS
Director, Ludwig Institute for Cancer Research, Princeton Branch, 01/2021-12/2025
Co-Investigator, NIH, 04/2022-03/2027
University of Pennsylvania Diabetes Research Center
Co-Investigator, DOE, 12/2022-11/2027
Center for Advanced Bioenergy and Bioproducts Innovation
Principal Investigator, Princeton Alliance for Collaborative Research & Innovation, 07/2023-06/2025
The impact of proteins & dietary fibers on the microbiome: Is digestibility the understudied
driver of metabolic dysregulation?
Co-Investigator, NIH/RBHS-CINJ-Cancer Center Support Grant, 03/2019-02/2024
Resource director for the Metabolomics Service for the CINJ
Principal Investigator, The Paul G. Allen Family Foundation, 12/2019-06/2023
Quantitative, Spatially-resolved Analysis of Tissue Metabolism
Principal Investigator, Calico Life Sciences, 01/2021-012/2023
Mechanisms of metabolic homeostasis in young and aged mice
Principal Investigator, Keio University/SU2C, 01/2021-12/2023
The Interplay of Diet, Microbiome, and Cancer Therapy
Principal Investigator, The Princeton Catalysis Initiative, 7/2020-6/2023
Cracking the localization code: Addressing small molecules to specific tissues and Organelles
Co-Investigator, The Princeton Catalysis Initiative, 07/2019-06/2023
The Language of Microbiome Sulfur Signaling
Co-Investigator, DOE, 09/2017-09/2023
Genome-scale Design & Engineering of Non-model Yeast Organisms for Production of Biofuels and Bioproducts
TEACHING
Undergraduate: A Quantitative, Integrative Introduction to the Sciences,
Parts V and VI (with D. Botstein and E. Wieschaus)
A uniquely mathematics-intensive introduction to genetics, physiology, and organic and biological chemistry for college sophomores
Graduate: Biophysical Chemistry I and II
A quantitatively rigorous treatment of biological chemistry for first year science graduate students
Chemical Biology II
A chemically and quantitatively rigorous treatment of metabolism and protein synthesis with a focus on modern advances and techniques
Organic Chemistry of Metabolism
An alternative to the traditional 2-semester sequence in organic chemistry, which teaches the most biologically important reactions through examples drawn from metabolism